Small Molecule Biomarker Core

Overview of Equipment and Services

The mission of the Small Molecule Biomarker Core (SMBC) is to facilitate researchers’ efforts to improve health via the quantitative analysis of small molecules.

The SMBC provides accurate and sensitive quantitative analysis in biological samples using state-of-the-art ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS). It offers comprehensive assay development and validation according to FDA bioanalytical guidelines and sample analysis (with or without sample processing). Analytical methods include numerous small molecule drug and metabolite panels such as antiretrovirals (eg, lenacapavir), endocrine markers (eg, estrogens), metformin, sildenafil, trimethylamine N-oxide (TMAO), and tetrahydrocannabinol (THC). A full list of methods with sample type can be found here.

Location and Hours of Operation

Primary: 223 Salk Pavilion, 335 Sutherland Dr., Pittsburgh, PA, 15261

Primary Sq. Ft: 419

Days of the Week

Hours open

Monday – Friday

8:00 am – 4:00 pm

Resources

Contacts

Name Role Phone Email Location
Raymond West, PhD
Assistant Director (Facility Director)
 
412-648-9854
 
rew82@pitt.edu
 
223 Salk Pavilion
 
Thomas Nolin, PharmD, PhD
Faculty Director
 

 
nolin@pitt.edu
 
206 Salk Pavilion
 
SMBC General email

 

 
biomarkers@pitt.edu
 
223 Salk Pavilion
 
Patrick Oberly
Core Staff
 

 
pjo7@pitt.edu
 
223 Salk Pavilion
 

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