ALERT

Register for our Shared Research Facilities Showcase!

Pitt’s shared research facilities house special-purpose equipment and offer expert consultation to support a wide range of technical areas across the University.

Join us to explore these facilities to enhance your research! Network with Pitt research specialists and discuss specific research questions.

As you explore the event, stop by each information table to grab a stamp on your Shared Research Facilities game board. Collect enough stamps and you'll be entered into our raffle for awesome prizes!

When: Monday, October 19th, 2026 from 2pm-5pm

Where: University Club, Ballroom B (second floor)

Who: Open to all Pitt faculty, students, and staff

Light appetizers and drinks will be provided.

Please register here: https://pitt.co1.qualtrics.com/jfe/form/SV_2srDXoGkJ933Nrw

Registration is Encouraged but not Required

(hide this warning on this page)

Health Sciences Sequencing Core

Overview of Equipment and Services

The Health Sciences Sequencing Core (HSSC) is located on the 8^th floor of the Rangos Research Building as part of the UPMC Children’s Hospital of Pittsburgh. Our facility offers next generation sequencing and spatial transcriptomics services to all University of Pittsburgh researchers. The HSSC operates two Illumina NextSeq 2000 instruments with Illumina DRAGEN servers that can generate up to 500Gb of sequence data per flow cell, and one MiSeq instrument for targeted resequencing, small genome, metagenomic and microbiome studies. For sample QC, our core utilizes a Fragment Analyzer (Agilent), Qubit Fluorometers (Invitrogen) and a TapeStation (Agilent). For spatial transcriptomics services, we offer end-to-end support for 10x Visium and 10x Xenium workflows. We operate two 10x Genomics CytAssist for Visium and Visium HD workflows, and one 10x Genomics Xenium Analyzer for running in situ Xenium workflows.

Location and Hours of Operation

Primary: Rangos Research Center-8145, 530 45^th St, Pittsburgh, PA, 15201

Primary Sq. Ft: 1350

Days of the Week	Hours open
Monday – Friday	9:00 am – 5:00 pm

Resources

Contacts

Name	Role	Email	Location
William MacDonald, PhD	Associate Director (Facility Director)	wam30@pitt.edu	Rangos Research Center 8145
Amanda C. Poholek, PhD	Faculty Director	poholeka@pitt.edu	The Assembly Building
HSSC General Email		hsscchp@pitt.edu
Rania Elbakri, MSc	Senior Research Staff	rania.elbakri@chp.edu	Rangos Research Center 8145
Yvette Rhodes	Senior Research Staff	ylr3@pitt.edu	Rangos Research Center 8145
Bryan Thompson	Senior Research Staff	brt2@pitt.edu	Rangos Research Center 8145
Yvonne Eisele, PhD	Senior Research Staff	eiseley@pitt.edu	Rangos Research Center 8145